Natural formulations have attracted great interest of many researchers regarding their use as latent fingermark developers powders due their important characteristics as the presence of natural pigments in these materials that offer a good contrast on the applied surface and also luminescent properties, which facilitates the visualization of minutiae in problematic substrates such as multicolored surfaces. In addition, natural powders present low toxicity, are widely available and economically viable. In this sense, the present work addresses the application of several natural products to enhance fingermarks visualization. The natural products were obtained from various sources such as seaweed, spices as well as other sources such as terrestrial and herbaceous plants. The evaluated powders are composed by compounds as chlorophyll, phycocyanins, curcumins, lawsone, fatty acids, coumarins, flavonoids and terpenes. These powders showed good adhesion to latent fingermarks, with similar or superior efficiency to the available powders on different surfaces with clear visualization of the minutiae. The development of new powders applicable to papiloscopy are extremely important since the conventional available powders, besides being expensive, are imported and within the national context there is a great lack of these revealing materials within forensic investigations by the Federal Police and in laboratories of research.

Fingerprints are unique to each individual, contributing to human identification in forensic cases. The powder technique being widely used is considered one of the most important in latent fingermarks analysis. In this sense, the present work aimed to synthesize 1-thiocarbamoyl-4,5-dihydro-1H-pyrazoles and apply them as powder agents to develop latent fingermarks. The compounds were prepared from an effective and green synthesis via the condensation of chalcones with thiosemicarbazide in ethanol under microwave irradiation. Pyrazoles were tested and compared with a standard white powder (Sirchie®) on glass surfaces using sebaceous and natural fingermarks so that molecule 2c has been shown to be more promising providing image clarity. The derivatives of pyrazoles were promising as an alternative latent fingermark, presenting high quality images for fingermarks, proving to be a great tool for forensic sciences.

The development of fingermarks is an important step in criminal cases. Latent fingermarks require applications of reagents to be developed before they can be visualized. Different techniques to enhance fingermarks’ visualization have been employed and the powder dusting is the most common among them. The use of food spices as latent fingermarks developers could be an alternative method of experiment in chemistry teaching, considering that they are low cost and accessible. In this work, an experimental methodology was developed and can be applied in undergraduate chemistry teaching for the extraction of components from food spices, their chromatographic analysis and application on the development of latent fingermarks.

Uma investigação fitoquímica de Polygala molluginifolia (raiz, caule, folhas e flores) resultou no isolamento de quatro piranoisoflavonas das quais a isoflavona1é desconhecida na literatura. As isoflavonas 2-4: , embora sejam compostos sintéticos conhecidos são descritos neste trabalho como novos produtos naturais. Os compostos isolados foram avaliados em termos do seu efeito antioxidante e o potencial para inibir a enzima acetilcolinesterase. As isoflavonas 1 e 4 inibiram a acetilcolinesterase, exibindo valores de IC50 de 68 µmol L-1 e 84 µmol L-1, respectivamente. No ensaio de DPPH, os mesmos compostos e a rutina 5 apresentaram valores de EC50 de 61 µmol L-1, 55 µmol L-1 e 16 µmol L-1, respectivamente. Além disso, a permeabilidade das compostos 1-4 foi testada através do ensaio de permeabilidade em membrana artificial paralela (PAMPA) com as isoflavona 3 (9.25 × 10-6 cm s-1) e 4 (3.48 × 10-6 cm s-1) exibindo as maiores permeabilidades.

A phytochemical investigation of Polygala molluginifolia (root, stem, leaves and flowers) resulted in the isolation of four pyranoisoflavones, of which isoflavone 1 was previously unknown in the literature. Isoflavones 2-4: , although they are known synthetic compounds, are described in this work as new natural products. The isolated compounds were evaluated for their antioxidant effects and potential for inhibiting the acetylcholinesterase enzyme. Isoflavones 1 and 4 inhibited acetylcholinesterase, displaying IC50 values of 68 µmol L-1 and 84 µmol L-1, respectively. In the DPPH assay, the same compounds and rutin 5 exhibited EC50 values of 61 µmol L-1, 55 µmol L-1 and 16 µmol L-1, respectively. Moreover, the permeability of compounds 1-4: was evaluated using parallel artificial membrane permeability assay (PAMPA) with isoflavones 3 (9.25 × 10-6 cm s-1) and 4 (3.48 × 10-6 cm s-1) exhibiting the highest permeabilities.

The discovery of ferrocene marked one of the points of departure for modern organometallic chemistry. In general, the compounds of ferrocene derivatives are widely applied in several areas. One of the most important applications of ferrocene is the development of more active drugs, especially in cases where there is resistance to current drugs. Bioactive agents containing ferrocene have proven effective in combating diseases such as cancer, malaria, HIV, Alzheimer and conditions caused by fungi and bacteria. In this context, the present paper aims to highlights the synthesis of heterocycles containing ferrocene moiety and their use in medicinal chemistry.

In this work we described the cultivation of Chlorella vulgaris in a photobioreactor to algal biomass production. The dried biomass was used as feedstock for biodiesel production, it presented 26% lipids and via sonocatalysis stage of the methodology resulted in 60% of fatty acid methyl esters (FAME). The FAME content was confirmed by Gas Chromatography (GC).